Saturday 21 January

Closamectin Pour On Solution for Cattle

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Closamectin Pour On is a clear, blue/green, ready-to-use solution containing:

Ivermectin 5mg/ml
Closantel (as closantel sodium) 200 mg/mL

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For the treatment of mixed trematode (fluke) and nematode or arthropod infestations due to roundworms, lungworms, eyeworms, warbles, mites and lice of cattle.

Gastrointestinal roundworms (adults and fourth stage larvae)
Ostertagia ostertagi (including inhibited O. ostertagi), Haemonchus placei, Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia spp, Oesophagostomum radiatum, Nematodirus helvetianus (adult), Strongyloides papillosus (adult).

Lungworms (adult and fourth stage larvae)
Dictyocaulus viviparus

Trematodes (adult and late immatures)
Fasciola gigantica
Fasciola hepatica

Treatment of fluke at 12 weeks (mature) >95% efficacy.
Treatment of fluke at 7 weeks (late immature) >95% efficacy.

Eyeworms (adult)
Thelazia spp

Cattle grubs (parasitic stages)
Hypoderma bovis, Hypoderma lineatum

Linognathus vituli, Haematopinus eurysternus, Damalinia bovis

Mange Mites
Chorioptes bovis, Sarcoptes scabiei var bovis

Dosage & Administration

The veterinary medicinal product should be administered topically at a dosage rate of 500 mg ivermectin per kg bodyweight and 20 mg closantel per kg bodyweight (1 mL per 10 kg).

The formulation should be applied along the midline of the back in a narrow strip between the withers and the tail head.

Assess bodyweight carefully prior to administration.

The timing for treatment should be based on epidemiological factors and should be customised for each individual farm. A dosing programme should be established by a veterinary professional.

Withdrawal Period

Cattle must not be treated within 28 days of slaughter for human consumption.

Not authorised for use in cattle producing milk for human consumption including during the dry period. Do not use during the second half of pregnancy in heifers which are intended to produce milk for human consumption.

Due to the significant likelihood of cross-contamination of non-treated animals with this product due to grooming (licking), all animals in a group should be treated at the same time and treated animals should be kept separately from non-treated animals throughout the withdrawal period. Non-compliance with this recommendation may lead to residues violations in non-treated animals.

Contraindictions, Warnings etc

Do not use in cases of known hypersensitivity to the active ingredients.

Do not apply to areas of skin which have mange, scabs or other lesions or to areas contaminated with mud or manure. Avermectins may not be well tolerated in non-target species (cases of intolerance with fatal outcome are reported in dogs – especially Collies, Old English Sheepdogs and related breeds or crosses, and also in turtles/tortoises).

Do not use in cases of known hypersensitivity to the active substances.

Do not apply to areas of skin which have mange, scabs or other lesions or to areas contaminated with mud or manure.

Pharmaceutical Precautions

Do not store above 25°C.
Store upright in original container.
Protect from light.
Discard unused material. Avoid introduction of contamination.
If stored at temperatures below 0°C, Closamectin Pour-On Solution for Cattle may appear cloudy. Allowing to warm at room temperature will restore the normal appearance without affecting efficacy.

Flammable – keep away from heat, sparks, open flame or other sources of ignition.


EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with the product or used container. Any unused product or waste material should be disposed of in accordance with national requirements.

Further Information

Click here for the SPC.

Please note: Product information presented on this website is intended only as a brief summary of Norbrook products for your convenience. Not all products or indications are licensed in every country and may be subject to further local variations. For specific product information you should always consult a healthcare professional from your region. Please see our terms and conditions for further information.

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