Noromectin® Plus Injection for Cattle (USA)

Presentation

Noromectin Plus is a ready-to-use sterile solution containing:
1% w/v ivermectin,
10% clorsulon,
40% glycerol formal,
propylene glycol, q.s. ad 100%.

Uses

Noromectin Plus Injection is indicated for the effective treatment and control of the following parasites in cattle:
Gastrointestinal Roundworms (adults and fourth-stage larvae):
Ostertagia ostertagi (including inhibited O. ostertagi)
O. lyrata
Haemonchus placei
Trichostrongylus axei
T. colubriformis
Cooperia oncophora
C. punctata
C. pectinata
Bunostomum phlebotomum
Nematodirus helvetianus (adults only)
N. spathiger (adults only)
Oesophagostomum radiatum
Lungworms (adults and fourth-stage larvae):
Dictyocaulus viviparus
Liver Flukes:
Fasciola hepatica (adults only)
Cattle Grubs (parasitic stages):
Hypoderma bovis
H. lineatum
Sucking Lice:
Linognathus vituli
Haematopinus eurysternus
Solenopotes capillatus
Mange Mites (cattle scab*):
Psoroptes ovis (syn. P. communis var. bovis)
Sarcoptes scabiei var. bovis

Dosage & Administration

Noromectin Plus is formulated to deliver the recommended dose level of 200 mcg ivermectin/kg and 2 mg clorsulon/kg given subcutaneously behind the shoulder at the rate of 1 mL per 110 lb (50 kg) body weight.

Withdrawal Period

Do not treat cattle within 49 days of slaughter. Because a withdrawal time in milk has not been established, do not use in female dairy cattle of breeding age. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.

Contraindictions, Warnings etc

For subcutaneous injection in cattle only.
This product is not for intravenous or intramuscular use.
Divide doses greater than 10 mL between two injection sites to reduce occasional discomfort or site reaction. Different injection sites should be used for other parenteral products.

ADVERSE REACTIONS:
Transitory discomfort has been observed in some cattle following subcutaneous administration. Soft-tissue swelling at the injection site has also been observed. These reactions have disappeared without treatment.
Noromectin Plus Injection has been developed specifically for use in cattle only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.

ADVICE ON CORRECT ADMINISTRATION
Noromectin Plus (ivermectin and clorsulon) Injection is to be given subcutaneously only. Animals should be appropriately restrained to achieve the proper route of administration. Use of a 16-gauge, 1/2" to 3/4" sterile needle is recommended. Inject the solution subcutaneously (under the skin) behind the shoulder.
Any single-dose syringe or standard automatic syringe equipment may be used with the 50 mL or 100 mL pack size.
When using the 250 mL, 500 mL or 1000 mL pack size, use only automatic syringe equipment.
Use sterile equipment and sanitize the injection site by applying a suitable disinfectant. Clean, properly disinfected needles should be used to reduce the potential for injection site infections.
No special handling or protective clothing is necessary.
The viscosity of the product increases in cool temperatures.
Administering Noromectin Plus at temperatures of 41°F (5°C) or below may be difficult. Users can make dosing easier by warming both the product and injection equipment to about 59°F (15°C).

Pharmaceutical Precautions

Protect product from light.
Store at 59° to 86°F (15° to 30°C).