Marbonor® 100 mg/ml Solution for Injection for Cattle and Pig
Clear yellow to amber solution for injection.
Each ml contains 100.0 mg Marbofloxacin
Treatment of respiratory infections caused by sensitive strains of
Pasteurella multocida, Mannheimia haemolytica and Mycoplasma bovis.
Treatment of acute mastitis caused by Echerichia coli strains sensitive to
marbofloxacin during the lactation period.
Treatment of Metritis Mastitis Agalactia Syndrome (postpartum
dysgalactia syndrome, PDS) caused by bacterial strains sensitive to
Dosage & Administration
The recommended dosage is 2 mg/kg (1 ml/50kg) in a single daily injection by intramuscular, subcutaneous or intravenous routes in cattle and by intramuscular route in pigs. For the injections, the neck should be preferred in cattle and pigs.
Treatment durations are 3 days in pigs and 3 to 5 days in cattle.
Advice On Correct Administration:
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible to avoid underdosing.
The vial may be broached up to 35 times. The user should choose the most appropriate vial size according to the target species to be treated.
Meat and offal: 6 days.
Milk: 36 hours
Pigs: Meat and offal: 4 days.
Contraindictions, Warnings etc
Do not use in cases where the pathogen involved is resistant to other fluoroquinolones (cross resistance).
Do not use in animals with known hypersensitivity to fluoroquinolones or to any of the excipients.
The efficacy data showed that the product has insufficient efficacy for the treatment of acute forms of mastitis induced by Gram-positive bacteria.
Administration by the intramuscular route may cause transient local reactions such as pain and swelling at the injection site and inflammatory lesions which may persist for at least 12 days after injection. However, in cattle subcutaneous route was shown to be better tolerated locally than intramuscular route. Therefore, the subcutaneous route is recommended in heavy cattle.
(i)Special precautions for use in animals. Official and local antimicrobial policies should be taken into account when the product is used. Fluoroquinolones should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials.
Whenever possible, fluoroquinolones should only be used based upon susceptibility testing. Use of the product deviating from the instructions
given in the SPC may increase the prevalence of bacteria resistant the fluoroquinolones and may decrease the effectiveness of treatment with
other quinolones due to the potential for cross resistance.
(ii)Special precautions to be taken by the person administering the veterinary medicinal product to animals.
People with known hypersensitivity to (fluoro)quinolones should avoid any contact with the veterinary medicinal product.
If the product comes into contact with skin or eyes, rinse with copious amounts of water.
Do not drink, eat or smoke whilst using the veterinary medicinal product.
Wash hands after use.
Accidental self-injection can induce a slight irritation.
In case of accidental self-injection or ingestion, seek medical advice immediately and show package leaflet or the label to the physician.
Do not store above 25°C.
Protect from light.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Click here to see the SPC.