Noromycin® 300 LA
(oxytetracycline injection)
Noromycin® 300 LA (oxytetracycline injection) is an effective, broad-spectrum and economical antibiotic for seasonal diseases in beef cattle, non-lactating dairy cattle and swine. Noromycin® 300 LA is now available with a higher dosing range for cattle (9 mg/lb -13.6 mg/lb as a single-dose treatment).
Target Species: Beef cattle, Non-Lactating dairy cattle, Calves, Including pre-ruminating (veal) calves, Swine
Product Attributes
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Higher flexible dosing ranges for cattle and swine:
§ Cattle: 13.6 mg/lb as a single IM/SQ dose or 9 mg/lb – 13 mg/lb as a single IM/SQ dose
§ Swine: 9 mg/lb as a single IM dose or 3 mg/lb – 5 mg/lb as a one-time daily IM dose
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With its higher flexible dosing, Noromycin® 300 LA is ideal for multiple treatment protocols, including the control of respiratory disease in cattle at high risk of developing BRD associated with Manheimia (Pasturella) haemolytica (when dosed at 13.6 mg/lb or 4.5 mL per 100 lbs of body weight as a single IM/SQ dose treatment).
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When dosed at 13.6 mg/lb or 4.5 mL per 100 lbs of body weight as a single IM/SQ dose, Noromycin® 300 LA stays above minimum inhibitory concentration (MIC) for at least 7-8 days against BRD associated with Manheimia (Pasturella) haemolytica
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Unique 300 mg/mL oxytetracycline
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Treats 33% more head per bottle*
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33% lower volume dose per injection*
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FDA approved
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Available in 100 mL, 250 mL and 500 mL vials
*When using 9 mg/lb dose, 300 mg/mL oxytetracycline provides 33% more doses than 200 mg/mL oxytetracycline
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Observe label directions and withdrawal times. Not for use in lactating dairy animals. Adverse reactions, including injection site swelling, restlessness, ataxia, trembling, respiratory abnormalities (labored breathing), collapse and possibly death have been reported. See product labeling for full product information.
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Active Ingredient(s)
300 mg/mL of oxytetracycline base
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Dosage Form
Sterile, pre-constituted solution for injection.
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Indications
Noromycin® 300 LA is intended for use in treatment for the following diseases when due to
oxytetracycline-susceptible organisms:
Beef cattle, non-lactating dairy cattle, calves, including pre-ruminating (veal) calves:
Noromycin® 300 LA is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp., and Histophilus spp. Noromycin® 300 LA is indicated for the treatment of infectious bovine keratoconjunctivitis (pink eye) caused by Moraxella bovis, foot-rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococcal and streptococcal organisms sensitive to oxytetracycline. Also, it is indicated for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia (Pasteurella) haemolytica.
Swine:
Noromycin® 300 LA is indicated in the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona.
In sows, Noromycin® 300 LA is indicated as an aid in control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
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Dosage and Administration
Beef cattle, non-lactating dairy cattle, calves, including pre-ruminating (veal) calves:
A single intramuscular or subcutaneous dosage of 13.6 mg of oxytetracycline per pound of bodyweight, Noromycin® 300 LA is recommended for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia (Pasteurella) haemolytica.
At a single intramuscular or subcutaneous dose range of 9 to 13.6 mg of oxytetracycline per pound of bodyweight, Noromycin® 300 LA is recommended in the treatment of the following conditions:
(1) Bacterial pneumonia caused by Pasteurella spp (shipping fever) in calves and yearlings where retreatment is impractical due to husbandry conditions, such as cattle on range, or where their repeated restraint is inadvisable.
(2) Infectious bovine kertaconjunctivitis (pink eye) caused by Moraxella bovis.
For other indications Noromycin® 300 LA is to be administered intramuscularly, subcutaneously or intravenously at a level of 3 to 5 mg of oxytetracycline per pound of bodyweight per day. In treatment of foot-rot and advanced cases of other indicated diseases, a dosage level of 5 mg per pound of bodyweight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four (4) consecutive days.
If improvement is not noted within 24 to 48 hours of the beginning of treatment, diagnosis and therapy should be re-evaluated.
Do not administer intramuscularly in the neck of small calves due to lack of sufficient muscle mass.
Use extreme care when administering this product by intravenous injection. Perivascular injection or leakage from an intravenous injection may cause severe swelling at the injection site.
Swine:
A single dosage of 9 mg of oxytetracycline per pound of bodyweight administered intramuscularly is recommended in the treatment of bacterial pneumonia caused by Pasteurella multocida in swine, where retreatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.
For the treatment of bacterial enteritis, pneumonia, and leptospirosis, administer 3 to 5 mg of oxytetracycline per pound of bodyweight per day by intramuscular injection. Treatment should be continued 24 to 48 hours following remission of disease signs; however, not to exceed a total of four (4) consecutive days. If improvement is not noted within 24 to 48 hours of the beginning of treatment, diagnosis and therapy should be re-evaluated.
For sows, administer once intramuscularly 3 mg of oxytetracycline per pound of bodyweight approximately eight (8) hours before farrowing or immediately after completion of farrowing as an aid in the control of infectious enteritis in baby pigs.
For swine weighing 25 lbs of bodyweight and under, Noromycin® 300 LA should be administered undiluted for treatment at 9 mg/lb but should be administered diluted for treatment at 3 or 5 mg/lb.
* To prepare dilutions, add one part of Noromycin 300 LA to three (3), five (5) or seven (7) parts of the sterile water, or 5% dextrose solution as indicated; the diluted product should be used immediately.
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Storage
Store at controlled room temperature 20-25°C. (68-77°F); excursions permitted 15-30°C (59-86°F). Protect from freezing. For 100 mL size: Use within 60 days of first puncture and puncture a maximum of 24 times. For 250 mL and 500 mL sizes: Use within 60 days of first puncture and puncture a maximum of 36 times. If using a needle or draw-off spike larger than 16 gauge, discard any remaining product immediately after use.
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Norbrook® now covers five classes of antibiotics
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Please note: Product information presented on this website is intended only as a brief summary of Norbrook products for your convenience. Not all products or indications are licensed in every country and may be subject to further local variations. For specific product information you should always consult a healthcare professional from your region or visit the local government agency website for the most up to date information. Please see our terms and conditions for further information.
